Highly stable amplified low-potential electrocatalytic detection of NAD+ at azure- chitosan modified carbon electrodes.

TANIN TANGKUARAM; JOSEPH WANG; MARCELA C. RODRÍGUEZ; RAWIWAN LAOCHAROENSUK; WARET VEERASAI

Elsevier

Lugar: Amsterdam; Año: 2007 vol. 121 p. 277 - 277

p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt; mso-layout-grid-align: none" class="MsoNormal">The incorporation of chitosan (CHIT) into an Azure-C (AZU) film, covering a glassy carbon electrode, greatly facilitates the electroreduction of NAD+ to allow a highly stable low-potential amplified cathodic detection of this enzymatic cofactor. Higher and sharper NAD+ reduction peaks are thus observed at lower potentials at the AZU/CHIT coated electrode, compared to those observed at the AZU-modified electrode. Such formation of an AZU/CHIT surface layer leads also to a highly stable NAD+ response. For example, 98% of the initial amperometric response of NAD+ at the AZU/CHIT coated electrode is retained after 20 min stirring 6